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The development of Nebula, the second and final stage of SETI@home data analysis, has made slow but steady progress. Check out the latest progress report: [Link] Improved multiplet-finding.
By seti@home at 2018-09-21
Congrats to all Rosetta@home volunteers who contributed to a recent report in Nature describing the design of a completely artificial fluorescent beta-barrel protein. As described by one of the main authors, Anastassia, [Link] in this forum post: The paper presents many “firsts” in computational protein design. It is the first de novo design of the beta-barrel fold (one of the most described folds in the past 35 years, yet mysterious until now). It is also the first de novo design of a protein tailored to bind a small-molecule, which requires very high accuracy in the placement of side chains on protein backbones assembled from scratch. Additionally, we could show that these new proteins could fold and function as expected in vivo! We hope that the advances described in the paper will further enable the de novo design of many biosensors and catalysts tailored for specific applications. Thanks to all the Rosetta@home volunteers who contributed to the validation of our designed proteins and binding sites. Here is the link to the IPD webpage that contains a copy of the paper. The work was also featured in the news articles below (the news in Science contains a video of one of our proteins glowing in living cells). [Link] https://www.bakerlab.org/index.php/2018/09/12/de-novo-fluorescent-proteins [rosetta@home at 2018-09-17
CRUNCHERS SANS FRONTIERES, one of World Community Grid's most dedicated teams, issues the THOR Challenge each fall. Find out how you and your team can join this year's challenge and beat last year's results.
By world community grid at 2018-09-17
From September 15th, 2018 Primegrid will be running a Cullen Challenge to celebrate Oktoberfest! The wold's biggest Volkfest is held annually in Munich, Bavaria, Germany, with more than six million people from around the world attending.
The 7 day Challenge starts at 18:00 UTC and ends on 22nd September exactly one week later at 18:00 UTC. Work units from the CUL (LLR) project, which are downloaded and completed during the challenge will count towards your challenge score.
The last Cullen Prime found was 6679881*2^6679881+1 from 2009. We're now testing numbers past 16M, so emotionally due for a prime.
For more information and discussion, please head over to the official challenge thread: [Link] http://www.primegrid.com/forum_thread.php?id=8194
By primegrid at 2018-09-15
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